Micky van de Ven Brace Ends Everton's Run at Brand New Stadium
The Dutch defender emerged as the initial defender to score two goals in a Premier League game for Tottenham since the Belgian defender in spring 2013.
Key points
Micky Van de Ven heads into the net twice in opening period
Everton's defender has equalizer ruled after video check
Senegalese midfielder nets third in dying moments
The defeat is the Merseyside club's first at Hill Dickinson Stadium
The Tottenham defender scored on two occasions as Spurs prolonged their winning streak in away games in the top division and delivered Everton their first defeat at their new home.
Everton were unbeaten in their last five matches at their recently opened stadium at Bramley-Moore Dock, having departed their historic home behind after more than a century at the conclusion of last season.
But Spurs captain Van de Ven pounced twice from set-pieces in the opening 45 minutes to put their strong form at risk, and they were unable to mount a comeback before Pape Matar Sarr - set up by ex-Everton forward the Brazilian - headed home a final goal to put the game to bed.
The Everton defender believed he had equalized the scores a short while after the defender's first goal, directing a powerful header past Guglielmo Vicario from an set-piece.
The Portuguese striker, meanwhile, failed to convert a handful of opportunities, while Vicario made a succession of fine saves to guarantee the London club went five away games without defeat in the Premier League.
But the VAR intervened, instructing the match official to review the goal on the screen and the referee decided that the winger and the attacker were in an illegal position and had impeded with the Tottenham goalkeeper.
The win elevates Thomas Frank's team up to third in the Premier League, five points off local foes and table-toppers the Gunners.
Everton stay 14th and are six points clear of the drop zone.
Tottenham analysis: The defender fulfils duties at each end of pitch
Following a uninspiring weekday performance in the European competition against the French side, where they managed a only attempts on target, the manager chose Randal Kolo Muani in attack instead of former Toffees player the Brazilian.
The new arrival was unable to influence the game before being replaced for the substitute after 60 minutes on the pitch, but it emerged he wasn't needed in the end.
Centre-back Van de Ven transformed into an attacking force to be feared.
Spurs' first goal came from a cleverly executed set-piece play, with Rodrigo Bentancur directing the ball back across the six-yard box for an free Van de Ven to head home.
And Ven de Ven - stepping up as skipper in Cristian Romero's unavailability - added his second in first-half stoppage time as he rose above the England keeper to head home.
Van de Ven was just as outstanding in defence, combining effectively with his defensive colleague as the duo dealt excellently with the 34 crosses thrown their way by Everton.
Everton analysis: Toffees missing striker's instinct
Everton's new home had been a fortress, but it seems the freshness may have faded slightly and supporters flocked to the exits after the midfielder's third for Spurs.
The break in Everton's unbeaten home run won't be a major worry for David Moyes, but their attacking woes are.
Beto and Thierno Barry - the Everton's two established centre-forwards - had netted only one league goal combined before the weekend's outing.
And they were unable to contribute to that miserable tally on a wet and gloomy night on in Liverpool.
The striker's form was summed up when he chose to overhead kick a clear chance from near the goal, despite having space and opportunity to reposition for a simpler shot that would have tested Vicario.
The substitute, too, was unable to make an impact after replacing Beto in the second half.
It was not for a shortage of opportunity. Most of the home side's offensive moves came through Grealish and Ndiaye, who tirelessly delivered dangerous crosses into the Spurs box.
What next for these two sides?
The Toffees: The team head to Sunderland in the top flight on Monday, 3 November at 20:00 GMT.
Spurs: Spurs go to St James' Park on late October for their fourth-round Carabao Cup tie against the Magpies.